diff --git a/README.md b/README.md
index 930fc43c..2fd661a8 100644
--- a/README.md
+++ b/README.md
@@ -380,6 +380,20 @@ the `content-length` header.
 }
 ```
 
+`onResponse` may also be async when you need to read the upstream response
+before sending a replacement body:
+
+```js
+{
+  async onResponse (request, reply, res) {
+    const data = await new Response(res.stream).json()
+    reply.send({ ...data, proxied: true })
+  }
+}
+```
+
+Handle errors inside async `onResponse` callbacks before replying.
+
 **Note**: `onResponse` is called after headers have already been sent. If you want to modify response headers, use the `rewriteHeaders` hook.
 
 #### `onError(reply, error)`
diff --git a/test/onResponse.test.js b/test/onResponse.test.js
index b442a71d..f3213ea4 100644
--- a/test/onResponse.test.js
+++ b/test/onResponse.test.js
@@ -40,3 +40,38 @@ t.test('onResponse', async (t) => {
   t.assert.strictEqual(result.statusCode, 200)
   t.assert.strictEqual(await result.body.text(), 'hello world')
 })
+
+t.test('async onResponse', async (t) => {
+  t.plan(6)
+
+  const instance = Fastify()
+  instance.register(From)
+  t.after(() => instance.close())
+
+  const target = http.createServer((req, res) => {
+    t.assert.ok('request proxied')
+    t.assert.strictEqual(req.method, 'GET')
+    res.statusCode = 200
+    res.end('hello world')
+  })
+
+  instance.get('/async', (request1, reply) => {
+    reply.from(`http://localhost:${target.address().port}`, {
+      async onResponse (request2, reply, res) {
+        await Promise.resolve()
+        t.assert.strictEqual(res.statusCode, 200)
+        t.assert.strictEqual(request1.raw, request2.raw)
+        reply.send(res.stream)
+      }
+    })
+  })
+
+  t.after(() => target.close())
+
+  await instance.listen({ port: 0 })
+  await new Promise(resolve => target.listen({ port: 0 }, resolve))
+
+  const result = await request(`http://localhost:${instance.server.address().port}/async`)
+  t.assert.strictEqual(result.statusCode, 200)
+  t.assert.strictEqual(await result.body.text(), 'hello world')
+})
diff --git a/types/index.d.ts b/types/index.d.ts
index 6a8fb272..c806ba28 100644
--- a/types/index.d.ts
+++ b/types/index.d.ts
@@ -75,7 +75,7 @@ declare namespace fastifyReplyFrom {
       request: FastifyRequest<RequestGenericInterface, RawServerBase>,
       reply: FastifyReply<RouteGenericInterface, RawServerBase>,
       res: RawServerResponse<RawServerBase>
-    ) => void;
+    ) => void | Promise<void>;
     onError?: (
       reply: FastifyReply<RouteGenericInterface, RawServerBase>,
       error: { error: Error }
diff --git a/types/index.tst.ts b/types/index.tst.ts
index 5e2bf6f8..d544bbd8 100644
--- a/types/index.tst.ts
+++ b/types/index.tst.ts
@@ -89,6 +89,16 @@ app.get('/v3', (_request, reply) => {
   })
 })
 
+app.get('/async-on-response', (_request, reply) => {
+  reply.from('/async-on-response', {
+    async onResponse (request, reply, res) {
+      expect(request).type.toBe<FastifyRequest<RequestGenericInterface, RawServerBase>>()
+      expect(reply).type.toBe<FastifyReply<RouteGenericInterface, RawServerBase>>()
+      expect(res).type.toBe<RawServerResponse<RawServerBase>>()
+    }
+  })
+})
+
 app.get('/http2', (_request, reply) => {
   reply.from('/', {
     method: 'POST',