diff --git a/.github/workflows/react_native.yml b/.github/workflows/react_native.yml
index f9d5be61e8743..215d906c6663e 100644
--- a/.github/workflows/react_native.yml
+++ b/.github/workflows/react_native.yml
@@ -275,14 +275,26 @@ jobs:
           ORT_C_LOCAL_POD_PATH=${{ runner.temp }}/ios_pod/onnxruntime-c pod install --verbose
         working-directory: ${{ github.workspace }}/js/react_native/e2e/ios
 
-      - name: Build and Run Detox iOS e2e Tests
+      - name: Build Detox iOS e2e Tests
+        run: detox build --configuration ios.sim.release
+        working-directory: ${{ github.workspace }}/js/react_native/e2e
+
+      - name: Reset iOS Simulators before Detox
+        run: |
+          set -e -x
+          xcrun simctl shutdown all || true
+          xcrun simctl erase all || true
+          killall Simulator || true
+          killall com.apple.CoreSimulator.CoreSimulatorService || true
+
+      - name: Run Detox iOS e2e Tests
         run: |
-          detox build --configuration ios.sim.release
           JEST_JUNIT_OUTPUT_FILE=${{ github.workspace }}/js/react_native/e2e/ios-test-results.xml \
             detox test --record-logs all \
                          --configuration ios.sim.release \
                          --loglevel verbose \
-                         --take-screenshots failing
+                         --take-screenshots failing \
+                         --cleanup
         working-directory: ${{ github.workspace }}/js/react_native/e2e
 
       - name: Upload iOS Test Results