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const labData = [
{
"region": "Global",
"country": "\ud83c\uddf8\ud83c\uddee Slovenia",
"institution": "National Institute of Chemistry (Slovenia)",
"pi": "Ajasja Ljubetic",
"image": "images/processed/Ajasja-Ljubetic.jpg",
"website": "https://ljubetic-lab.si/",
"papers": [],
"keywords": "De novo protein design, dynamic protein assemblies, coiled coils, protein robotics, computational modeling, Rosetta software, protein engineering.",
"about": "This research focuses on designing and studying dynamic protein assemblies, particularly coiled coil structures. The lab uses the Rosetta software to rigidly fuse coiled coils with de novo designed proteins, enabling controlled motion and developing protein-based robots. Current projects include engineering rigidified protein assemblies for active walking and exploring applications of these scaffolds in protein robotics.",
"hiringStatus": "closed"
},
{
"region": "Global",
"country": "\ud83c\udde9\ud83c\uddea Germany",
"institution": "Ludwig Maximilian University of Munich",
"pi": "Alena Khmelinskaia",
"image": "images/processed/Alena-Khmelinskaia.jpg",
"website": "https://khmelinskaia.cup.uni-muenchen.de/",
"papers": [],
"keywords": "Protein self-assembly, de novo protein design, biophysical methods, structural flexibility, dynamic protein materials, cargo encapsulation.",
"about": "This research focuses on understanding the physical principles of protein self-assembly. By integrating computational de novo protein design, protein production, and biophysical methods, the lab investigates the interactions governing assembly dynamics. The work explores structural flexibility to develop dynamic and responsive protein-based materials for applications such as support coating and cargo encapsulation.",
"hiringStatus": "open",
"jobsUrl": "https://khmelinskaia.cup.uni-muenchen.de/jobs-and-opportunities/"
},
{
"region": "EMEA",
"country": "\ud83c\udde6\ud83c\uddf9 Austria",
"institution": "AITHYRA Research Institute for Biomedical Artificial Intelligence",
"pi": "Alexander Tong",
"image": "images/processed/Alexander-Tong.jpg",
"website": "https://www.alextong.net/",
"papers": []
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Butler University",
"pi": "Alican Gulsevin",
"image": "images/processed/Alican-Gulsevin.jpg",
"website": "https://gulsevinlab.org/",
"papers": [],
"keywords": "Computational modeling, membrane proteins, protein interactions, structural biology, genomic data, human health.",
"about": "This research focuses on computational modeling of proteins involved in human health by integrating experimental and genomic data. The lab studies membrane proteins and their interactions with peptides and small molecules using structural biology applications and in-house methods to analyze how structural changes influence protein interactions.",
"hiringStatus": "open",
"jobsUrl": "https://gulsevinlab.org/openings/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Massachusetts Institute of Technology",
"pi": "Amy E. Keating",
"image": "images/processed/Amy-E-Keating.jpg",
"website": "https://biology.mit.edu/profile/amy-e-keating/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://www.keatinglab.mit.edu/positions"
},
{
"region": "Global",
"country": "\ud83c\udde7\ud83c\uddea Belgium",
"institution": "Vrije Universiteit Brussel",
"pi": "Anastassia A. Vorobieva",
"image": "images/processed/Anastassia-A-Vorobieva.jpg",
"website": "https://vorobievalab.sites.vib.be/en",
"papers": [
{
"title": "Nanopore design",
"url": "https://www.science.org/doi/10.1126/science.adn3796"
}
],
"keywords": "Membrane proteins, transmembrane beta-barrels, computational protein design, nanopore engineering, protein stability, single-molecule sensing, beta-barrel vaccines.",
"about": "This lab focuses on de novo design of membrane proteins, specifically transmembrane beta-barrels. Research includes computational methods to create beta-barrels with novel properties and structures, as well as developing experimental validation approaches. Applications include engineered nanopores for single-molecule sensing and beta-barrel-based vaccines targeting Gram-negative bacteria.",
"hiringStatus": "open",
"jobsUrl": "https://vorobievalab.sites.vib.be/en/jobs"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Chicago",
"pi": "Andrew Ferguson",
"image": "images/processed/Andrew-Ferguson.jpg",
"website": "https://pme.uchicago.edu/faculty/andrew-ferguson",
"papers": [],
"hiringStatus": "closed",
"jobsUrl": "https://www.ferglab.com/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "UCSC",
"pi": "Andy Hsien-Wei Yeh",
"image": "images/processed/Andy-Hsien-Wei-Yeh.jpg",
"website": "https://neolux.sites.ucsc.edu/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://neolux.sites.ucsc.edu/"
},
{
"region": "EMEA",
"country": "\ud83c\udde8\ud83c\udded Switzerland",
"institution": "EPFL",
"pi": "Anne-Florence Bitbol",
"image": "images/processed/Anne-Florence-Bitbol.jpg",
"website": "https://www.epfl.ch/labs/bitbol-lab/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://www.epfl.ch/labs/bitbol-lab/join-us/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Wisconsin-Madison",
"pi": "Anthony Gitter",
"image": "images/processed/Anthony-Gitter.jpg",
"website": "https://www.biostat.wisc.edu/~gitter/",
"papers": [],
"hiringStatus": "closed",
"jobsUrl": "https://www.biostat.wisc.edu/~gitter/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Columbia University",
"pi": "Anum Glasgow",
"image": "images/processed/Anum-Glasgow.jpg",
"website": "https://www.biochem.cuimc.columbia.edu/profile/anum-glasgow-phd",
"papers": [],
"keywords": "Computational protein design, biophysical techniques, conformational switching, signal-responsive proteins, protein engineering, ligand binding, therapeutic proteins.",
"about": "This research integrates computational protein design with high-throughput biophysics to engineer proteins that change conformation in response to signals. By developing design principles for signal-responsive proteins, the lab aims to control cellular behavior and develop targeted therapeutics. Long-term goals include engineering multifunctional proteins for precise ligand binding and localization, advancing disease treatment strategies.",
"hiringStatus": "open",
"jobsUrl": "https://glasgowlab.org/1_intro.html"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Vanderbilt University",
"pi": "Ben Brown",
"image": "images/processed/Ben-Brown.jpg",
"website": "https://www.bpbrownlab.org/",
"papers": [],
"keywords": "Protein dynamics, signal transduction, enzyme catalysis, molecular recognition, AI-driven drug design, induced-fit modeling, virtual screening, disease mutations.",
"about": "This research explores how protein dynamics influence biological function, disease, and drug response. By integrating physics-based and AI-driven methods, the lab designs small molecules targeting flexible proteins. Key areas include modeling large-scale induced-fit changes for high-throughput virtual screening and analyzing disease mutations to guide therapeutic decision-making in collaboration with clinicians."
},
{
"region": "EMEA",
"country": "\ud83c\udde9\ud83c\uddea Germany",
"institution": "University of Bayreuth",
"pi": "Birte H\u00f6cker",
"image": "images/processed/Birte-H\u00f6cker.jpg",
"website": "https://www.proteindesign.uni-bayreuth.de/en/index.html",
"papers": [],
"keywords": "Protein evolution, protein design, small molecule receptors, enzymes, biosensors, molecular machines, artificial motor proteins, small molecule binding.",
"about": "This lab designs small molecule receptors, enzymes, and artificial motor proteins. Research focuses on protein evolution, molecular machines, biosensors, and the principles underlying small molecule binding."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Stanford University",
"pi": "Brian Hie",
"image": "images/processed/Brian-Hie.jpg",
"website": "https://evodesign.org/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://evodesign.org/join"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "UNC Chapel Hill",
"pi": "Brian Kuhlman",
"image": "images/processed/Brian-Kuhlman.jpg",
"website": "https://klab.web.unc.edu/research/",
"papers": [],
"keywords": "Protein design, protein-protein interactions, computational modeling, experimental validation, Rosetta, vaccine design, structural biology.",
"about": "This research focuses on designing proteins and protein interactions using a combination of computational and experimental methods. Current work includes developing novel protein-protein interactions, protein structures, and light subunit vaccines. The Rosetta program is central to these efforts, with ongoing contributions to its development and application in new protein modeling challenges.",
"hiringStatus": "open",
"jobsUrl": "https://klab.web.unc.edu/join/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Stanford University",
"pi": "Brian Trippe",
"image": "images/processed/Brian-Trippe.jpg",
"website": "https://briantrippe.com/",
"papers": [],
"hiringStatus": "closed",
"jobsUrl": "https://briantrippe.com/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Duke University",
"pi": "Bruce Donald",
"image": "images/processed/Bruce-Donald.jpg",
"website": "https://users.cs.duke.edu/~brd/",
"papers": []
},
{
"region": "EMEA",
"country": "\ud83c\udde8\ud83c\udded Switzerland",
"institution": "EPFL Lausanne",
"pi": "Bruno E. Correia",
"image": "images/processed/Bruno-E-Correia.jpg",
"website": "https://www.epfl.ch/labs/lpdi/",
"papers": [],
"keywords": "Protein design, functional proteins, therapeutics, vaccines, biosensors, synthetic biology.",
"about": "The Correia Group designs novel functional proteins to expand nature's capabilities for practical applications, including therapeutics, vaccines, and biosensors. By engineering proteins with tailored properties, the lab advances synthetic biology to address biomedical and biotechnological challenges.",
"hiringStatus": "open",
"jobsUrl": "https://www.epfl.ch/labs/lpdi/page-121368-en-html/"
},
{
"region": "Asia",
"country": "\ud83c\uddf0\ud83c\uddf7 South Korea",
"institution": "Korea Advanced Institute of Science & Technology",
"pi": "Byung-Ha Oh",
"image": "images/processed/Byung-Ha-Oh.jpg",
"website": "https://sites.google.com/view/tpdsb/home?authuser=0",
"papers": [],
"keywords": "Computational protein design, antibody engineering, protein-protein interactions, protein binders, molecular modeling, therapeutic proteins.",
"about": "This research focuses on computational design of therapeutic proteins and protein binders. Projects include designing antibodies, creating novel proteins that target specific interactions, and enhancing the binding properties of existing proteins. The lab uses computational modeling to precisely engineer protein interactions and improve therapeutic effectiveness"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Rice University",
"pi": "Cameron Glasscock",
"image": "images/processed/Cameron-Glasscock.jpg",
"website": "https://glasscocklab.blogs.rice.edu/",
"papers": [],
"keywords": "Protein design, protein-nucleic acid interactions, synthetic biology, artificial intelligence, machine learning, high-throughput biochemistry, functional assays.",
"about": "This lab develops computational methods for predicting and designing protein-nucleic acid assemblies using physics-based modeling and AI/ML approaches. Research incorporates high-throughput biochemistry, molecular biology, and sequencing technologies, emphasizing advanced protein functional assays to support AI-driven protein design.",
"hiringStatus": "open",
"jobsUrl": "https://glasscocklab.blogs.rice.edu/join/"
},
{
"region": "Global",
"country": "\ud83c\udde8\ud83c\uddf1 Chile",
"institution": "Pontificia Universidad Catolica de Chile",
"pi": "Cesar Ramirez-Sarmiento",
"image": "images/processed/Cesar-Ramirez-Sarmiento.jpg",
"website": "NA",
"papers": [],
"keywords": "Protein engineering, computational modeling, metamorphic proteins, PET hydrolysis, enzyme evolution, synthetic biology, oxygen carriers, photosynthetic microorganisms.",
"about": "This research employs experimental and computational strategies to study metamorphic proteins and bacterial enzymes capable of hydrolyzing PET plastics. The lab investigates protein evolution, stability, and design, and uses synthetic biology approaches to engineer photosynthetic microorganisms into oxygen carriers."
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "University of Oxford",
"pi": "Charlotte Deane",
"image": "images/processed/Charlotte-Deane.jpg",
"website": "https://opig.stats.ox.ac.uk/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://opig.stats.ox.ac.uk/"
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "University of Edinburgh",
"pi": "Chris Wells Wood",
"image": "images/processed/Chris-Wells-Wood.jpg",
"website": "https://www.wellswoodresearchgroup.com/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://www.wellswoodresearchgroup.com/"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Rensselaer Polytechnic Institute",
"pi": "Christopher Bystroff",
"image": "images/processed/Christopher-Bystroff.jpg",
"website": "https://www.bioinfo.rpi.edu/bystrc/",
"papers": [],
"keywords": "Protein folding, protein design, green fluorescent protein (GFP), fluorescent biosensors, molecular dynamics, biophysical analysis, X-ray crystallography.",
"about": "This research explores protein folding pathways to improve protein design algorithms. A major focus is on green fluorescent protein (GFP), studying its folding and dynamics to develop programmable fluorescent biosensors for detecting peptides and proteins. The lab develops high-performance computational software and validates designed molecules through biophysical analysis and X-ray crystallography."
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Peking University",
"pi": "Chu Wang",
"image": "images/processed/Chu-Wang.jpg",
"website": "https://www.chem.pku.edu.cn/wangchulab/",
"papers": [],
"keywords": "Protein docking, metal-binding proteins, chemoproteomics, bioinformatics, metabolic regulation, enzyme function, computational biology.",
"about": "This lab combines chemoproteomics, bioinformatics, and computational structural biology to discover functional enzyme sites modified by metabolites or drugs. The group investigates molecular mechanisms regulating enzyme functions and develops computational methods to predict protein-small molecule interactions."
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Tsinghua University",
"pi": "Chunfu Xu",
"image": "images/processed/Chunfu-Xu.jpg",
"website": "https://www.timbr.tsinghua.edu.cn/info/1752/3158.htm",
"papers": [],
"keywords": "Protein design, protein-nucleic acid interactions, synthetic biology, artificial intelligence, machine learning, high-throughput biochemistry, functional assays.",
"about": "This lab develops computational protein design methods to engineer novel proteins, including fluorescent proteins, transmembrane proteins, and enzymes. The designed proteins serve as tools and devices in fundamental research, biotechnology, and medical applications."
},
{
"region": "Global",
"country": "\ud83c\udde9\ud83c\uddea Germany",
"institution": "Leipzig University",
"pi": "Clara T. Schoeder",
"image": "images/processed/Clara-T-Schoeder.jpg",
"website": "https://www.schoederlab.org/",
"papers": [
{
"title": "Combine Rosetta and ESM",
"url": "https://pubs.acs.org/doi/10.1021/acssynbio.3c00753"
}
],
"keywords": "Computational protein design, immunotherapeutics, Adeno-associated virus (AAV), chimeric antigen receptors (CARs), single-chain variable fragments (scFvs), vaccine design, epitope focusing, pharmacokinetics.",
"about": "This research focuses on computational protein design methods for developing novel immunotherapeutic drugs. The lab studies Adeno-associated virus (AAV) interactions, designs cellular therapeutics such as chimeric antigen receptors (CARs), optimizes antibody fragments (scFvs), and develops vaccine candidates through stabilization and epitope focusing.",
"hiringStatus": "open",
"jobsUrl": "https://www.schoederlab.org/our-team"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Wesleyan University",
"pi": "Colin Smith",
"image": "images/processed/Colin-Smith.jpg",
"website": "https://smithlab.research.wesleyan.edu/",
"papers": [],
"keywords": "Protein structure, atomic-level mechanisms, second-shell interactions, structural propagation, protein conformational changes, therapeutic protein engineering, structural biology.",
"about": "The Smith Lab investigates atomic-level mechanisms underlying structural rearrangements in proteins, specifically how changes propagate from one region to another. The lab addresses questions of structural communication and how subtle rearrangements influence protein behavior and functionality.",
"hiringStatus": "open",
"jobsUrl": "https://smithlab.research.wesleyan.edu/joining/"
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "University of Leeds",
"pi": "Darren Tomlinson",
"image": "images/processed/Darren-Tomlinson.jpg",
"website": "https://astbury.leeds.ac.uk/people/dr-darren-tomlinson/",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Washington",
"pi": "David Baker",
"image": "images/processed/David-Baker.jpg",
"website": "https://www.bakerlab.org/",
"papers": [],
"keywords": "De novo protein design, hyperstable proteins, vaccine design, RFdiffusion, protein structure, enzyme catalysis, self-assembling nanomaterials, drug delivery, Top7, Nobel Prize.",
"about": "This research pioneered de novo protein design with TOP7 and developed principles for designing hyper stable proteins with diverse folds. Stabilizing pathogen epitopes enables computational vaccine development. The lab's RFdiffusion model advances protein design, creating complex structures. Ongoing work includes designing novel enzymes and self-assembling nanomaterials for drug delivery and vaccines.",
"hiringStatus": "open",
"jobsUrl": "https://www.ipd.uw.edu/join-us/"
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "University of Leeds",
"pi": "David Brockwell",
"image": "images/processed/David-Brockwell.jpg",
"website": "https://astbury.leeds.ac.uk/people/dr-david-brockwell/",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Duke University",
"pi": "David C. Richardson & Jane Shelby Richardson",
"image": "images/processed/David-C-Richardson-&-Jane-Shelby-Richardson.jpg",
"website": "https://www.biochem.duke.edu/people/richardson-lab",
"papers": [],
"hiringStatus": "closed",
"jobsUrl": "http://kinemage.biochem.duke.edu/"
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "University College London",
"pi": "David T. Jones",
"website": "http://www0.cs.ucl.ac.uk/staff/d.jones/",
"papers": []
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "University of Bristol",
"pi": "Dek Woolfson",
"image": "images/processed/Dek-Woolfson.jpg",
"website": "https://woolfsonlab.wordpress.com/",
"papers": []
},
{
"region": "Global",
"country": "\ud83c\uddf5\ud83c\uddf1 Poland",
"institution": "University of Warsaw",
"pi": "Dominik Gront",
"image": "images/processed/Dominik-Gront.jpg",
"website": "https://bioshell.pl/home",
"papers": [],
"keywords": "Structural bioinformatics, coarse-grained modeling, multiscale modeling, algorithm development, biomolecular dynamics, BioShell software.",
"about": "This research develops computational methods for multiscale modeling of biomacromolecular structure and dynamics. The lab creates coarse-grained approaches to study proteins at different resolution levels and develops the BioShell software suite for structural bioinformatics, including alignments, modeling, analysis, and visualization of biomolecular structures.",
"hiringStatus": "closed",
"jobsUrl": "https://bioshell.pl/"
},
{
"region": "EMEA",
"country": "\ud83c\udde8\ud83c\udded Switzerland",
"institution": "ETH Zurich",
"pi": "Donald Hilvert",
"image": "images/processed/Donald-Hilvert.jpg",
"website": "https://protein.ethz.ch/",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "University of Chinese Academy of Sciences",
"pi": "Dongbo Bu",
"image": "images/processed/Dongbo-Bu.jpg",
"website": "https://people.ucas.edu.cn/~dbu",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "St. Jude Children\u2019s Research Hospital",
"pi": "Elizabeth H. Kellogg",
"image": "images/processed/Elizabeth-H-Kellogg.jpg",
"website": "kellogglab.org",
"papers": [],
"keywords": "Molecular organization, nucleic acid interactions, dynamic complexes, Rosetta, cryo-EM, structural biology.",
"about": "This research focuses on understanding how cells organize molecular information by studying dynamic complexes that interact with nucleic acids. Using Rosetta and cryo-EM, the lab interprets atomic-level structures to gain insights into their biological functions."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Princeton University",
"pi": "Ellen D. Zhong",
"image": "images/processed/Ellen-D-Zhong.jpg",
"website": "https://www.cs.princeton.edu/~zhonge/",
"papers": []
},
{
"region": "EMEA",
"country": "\ud83c\uddea\ud83c\uddf8 Spain",
"institution": "Institute of Molecular Biology of Barcelona CSIC",
"pi": "Enrique Marcos",
"image": "images/processed/Enrique-Marcos.jpg",
"website": "https://ibmb.csic.es/en/department-of-structural-and-molecular-biology/protein-design-and-modeling/#lab-presentation",
"papers": [
{
"title": "de novo immunoglobulin design",
"url": "https://www.nature.com/articles/s41467-023-41717-5"
}
],
"hiringStatus": "open",
"jobsUrl": "https://ibmb.csic.es/en/department-of-structural-and-molecular-biology/protein-design-and-modeling/#vacancies-jobs"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Washington University of St. Louis",
"pi": "Eva-Maria Strauch",
"image": "images/processed/Eva-Maria-Strauch.jpg",
"website": "http://www.strauchlab.com/",
"papers": [],
"keywords": "Protein engineering, viral proteins, structural design, oligo-synthesis, next-generation sequencing, immunogen design, protein chemistry.",
"about": "This research group studies viral surface proteins using structural design and high-throughput techniques to develop therapeutic and immunological interventions. The lab aims to understand viral protein chemistry and design novel immunogens targeting viral infections.",
"hiringStatus": "open",
"jobsUrl": "http://www.strauchlab.com/join.html"
},
{
"region": "EMEA",
"country": "\ud83c\uddec\ud83c\udde7 United Kingdom",
"institution": "Cardiff University",
"pi": "Fabio Parmeggiani",
"image": "images/processed/Fabio-Parmeggiani.jpg",
"website": "https://profiles.cardiff.ac.uk/staff/parmeggianif",
"papers": [
{
"title": "Repeat protein design",
"url": "https://www.nature.com/articles/nature16162"
}
],
"keywords": "Hybrid computational-experimental methods, protein design, repeat proteins, modular systems, nanomaterials, spatial control, cellular behavior.",
"about": "This research develops hybrid computational and experimental approaches to protein design, focusing on modular systems composed of designed repeat proteins. The lab explores spatial control of protein structures for applications ranging from nanomaterials to tools influencing and studying cellular behavior."
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Westlake University",
"pi": "Fajie Yuan",
"image": "images/processed/Fajie-Yuan.jpg",
"website": "https://fajieyuan.github.io/",
"papers": []
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Massachusetts Dartmouth",
"pi": "Firas Khatib",
"image": "images/processed/Firas-Khatib.jpg",
"website": "https://www.cis.umassd.edu/~fkhatib/",
"papers": [],
"keywords": "Citizen science, crowdsourcing, computational biology, public engagement, scientific problem-solving.",
"about": "This research focuses on engaging the public in solving complex scientific problems through citizen science and crowdsourcing. By leveraging collective human intelligence, the lab addresses critical challenges in computational biology."
},
{
"region": "Global",
"country": "\ud83c\udde6\ud83c\uddf9 Austria",
"institution": "Institute of Science and Technology Austria",
"pi": "Florian Praetorius",
"image": "images/processed/Florian-Praetorius.jpg",
"website": "https://ista.ac.at/en/research/praetorius-group/",
"papers": [],
"keywords": "Protein design, DNA origami, nucleic acids, deep learning, ProteinMPNN, Rosetta, biomolecular assemblies.",
"about": "The Praetorius lab develops computational design tools, including deep learning and physics-based methods, to engineer proteins and nucleic acids. They experimentally characterize de novo proteins and aim to create DNA-protein hybrid assemblies with novel functions for applications in biosensing, gene delivery, gene editing, and vaccine development.",
"hiringStatus": "closed",
"jobsUrl": "https://ista.ac.at/en/research/praetorius-group/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Caltech",
"pi": "Frances Arnold",
"image": "images/processed/Frances-Arnold.jpg",
"website": "http://fhalab.caltech.edu/",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Washington",
"pi": "Frank Dimaio",
"image": "images/processed/Frank-Dimaio.jpg",
"website": "https://dimaiolab.ipd.uw.edu/",
"papers": [],
"keywords": "Structure determination, crystal structure refinement, conformational sampling, protein force fields, computational modeling, experimental data analysis.",
"about": "This research focuses on developing methods for determining protein structures from sparse and noisy experimental data. Key areas include crystal structure refinement, conformational sampling, and protein force field development. By integrating computational modeling with experimental analysis, the lab enhances accuracy in protein structure prediction and refinement."
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Northwestern University",
"pi": "Gabriel Rocklin",
"image": "images/processed/Gabriel-Rocklin.jpg",
"website": "http://www.rocklinlab.org/",
"papers": [],
"keywords": "High-throughput protein design, computational modeling, protein biophysics, protein therapeutics, display selections, mass spectrometry proteomics, next-generation sequencing, protein stability, conformational dynamics.",
"about": "This research develops high-throughput methods for protein design and biophysics, focusing on protein therapeutics. The lab combines large-scale computational modeling with experimental approaches, including display selections, mass spectrometry proteomics, and next-generation sequencing, to study protein folding, stability, dynamics, and resistance to aggregation.",
"hiringStatus": "open",
"jobsUrl": "http://www.rocklinlab.org/#join"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Washington",
"pi": "Gaurav Bhardwaj",
"image": "images/processed/Gaurav-Bhardwaj.jpg",
"website": "https://peptidedesign.org/",
"papers": [],
"keywords": "Peptide drug design, computational modeling, antibiotics, antivirals, anti-cancer peptides, cellular permeability, oral bioavailability, machine learning.",
"about": "This research develops computational and experimental methods to design therapeutic peptides with high specificity and stability. Focus areas include designing antibiotics, antivirals, and anti-cancer peptides, as well as enhancing cellular permeability and oral bioavailability. Machine learning-based approaches are also employed to generate peptides with diverse structures and functions.",
"hiringStatus": "open",
"jobsUrl": "https://peptidedesign.org/members"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Illinois at Urbana-Champaign",
"pi": "Ge Liu",
"image": "images/processed/Ge-Liu.jpg",
"website": "https://www.mit.edu/~geliu/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://www.mit.edu/~geliu/"
},
{
"region": "Global",
"country": "\ud83c\udde9\ud83c\uddea Germany",
"institution": "Leipzig University",
"pi": "Georg Kuenze",
"image": "images/processed/Georg-Kuenze.jpg",
"website": "https://kuenzelab.org/",
"papers": [],
"keywords": "Protein modeling, membrane proteins, signaling mechanisms, enzyme design, molecular dynamics, molecular signaling, biotechnology, biophysics, drug targeting.",
"about": "This research combines computational modeling and biophysical experiments to study molecular signaling in membrane proteins, design enzymes for biotechnology, and understand protein-drug interactions. Using molecular dynamics simulations alongside experimental validation, the lab investigates signaling mechanisms, designs improved enzymes, and identifies small-molecule drugs targeting membrane proteins."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Harvard University",
"pi": "George Church",
"image": "images/processed/George-Church.jpg",
"website": "https://wyss.harvard.edu/team/core-faculty/george-church/",
"papers": [],
"hiringStatus": "closed",
"jobsUrl": "https://arep.med.harvard.edu/"
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Zhejiang University of Technology",
"pi": "Guijun Zhang",
"image": "images/processed/Guijun-Zhang.jpg",
"website": "http://zhanglab-bioinf.com/people/guijunz/",
"papers": []
},
{
"region": "EMEA",
"country": "\ud83c\udde6\ud83c\uddf9 Austria",
"institution": "Graz University of Technology",
"pi": "Gustav Oberdorfer",
"image": "images/processed/Gustav-Oberdorfer.jpg",
"website": "https://www.tugraz.at/institute/ibc/research/research-groups/protein-design",
"papers": [
{
"title": "Helical Bundle design",
"url": "https://www.science.org/doi/abs/10.1126/science.1257481"
},
{
"title": "ESM-Scan",
"url": "https://www.biorxiv.org/content/10.1101/2023.12.12.571273v2"
}
],
"keywords": "De novo protein design, enzyme design, biomedical applications, biotechnology, computational modeling, protein engineering, structural biology.",
"about": "This research group focuses on de novo protein design, developing and broadening state-of-the-art methodologies for biomedical and biotechnological applications. Current projects include designing novel enzymes and proteins with specific geometries. The lab combines computational approaches with structural biology to expand the functional repertoire of engineered proteins.",
"hiringStatus": "closed",
"jobsUrl": "https://www.tugraz.at/institute/ibc/research/research-groups/protein-design/group-members"
},
{
"region": "Global",
"country": "\ud83c\uddf0\ud83c\uddf7 South Korea",
"institution": "Korea Advanced Institute of Science and Technology",
"pi": "Gyu Rie Lee",
"image": "images/processed/Gyu-Rie-Lee.jpg",
"website": "https://pure.kaist.ac.kr/en/persons/gyurie-lee/",
"papers": [],
"keywords": "Protein design, deep learning, small molecules, epigenetics, post-translational modifications.",
"about": "This lab develops AI-based methods for protein design, specifically targeting epigenetic processes and chemical modifications of peptides and nucleic acids. Research aims to create custom-designed protein tools and explore therapeutic applications focused on epigenetic mechanisms and cellular metabolism.",
"hiringStatus": "closed",
"jobsUrl": "https://pure.kaist.ac.kr/en/persons/gyurie-lee/"
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Shanghai Jiao Tong University",
"pi": "Haifeng Cheng",
"image": "images/processed/Haifeng-Cheng.jpg",
"website": "https://cbb.sjtu.edu.cn/~hfchen/",
"papers": [
{
"title": "Sequence design benchmark",
"url": "https://doi.org/10.1093/bioinformatics/btae037"
}
]
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Tsinghua University",
"pi": "Haipeng Gong",
"image": "images/processed/Haipeng-Gong.jpg",
"website": "https://structpred.life.tsinghua.edu.cn/",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "University of Science and Technology of China",
"pi": "Haiyan Liu",
"image": "images/processed/Haiyan-Liu.jpg",
"website": "https://biocomp.ustc.edu.cn/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://biocomp.ustc.edu.cn/join_us.html"
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Tsinghua University",
"pi": "Hao Zhou",
"image": "images/processed/Hao-Zhou.jpg",
"website": "https://zhouh.github.io/",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\uddf0\ud83c\uddf7 South Korea",
"institution": "Institute for Basic Science",
"pi": "Ho Min Kim",
"image": "images/processed/Ho-Min-Kim.jpg",
"website": "https://protein.ibs.re.kr/people/chief-investigator",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://sites.google.com/view/phcholab/contact?authuser=0"
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Shanghai Jiao Tong University",
"pi": "Hongbin Shen",
"image": "images/processed/Hongbin-Shen.jpg",
"website": "http://www.csbio.sjtu.edu.cn/",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences",
"pi": "Huifeng Jiang",
"image": "images/processed/Huifeng-Jiang.jpg",
"website": "http://www.tib.cas.cn/sourcedb_tib_cas/cn/expert/rckyjy/201212/t20121212_3704580.html",
"papers": [
{
"title": "DeepEvo",
"url": "https://spj.science.org/doi/full/10.34133/bdr.0031"
},
{
"title": "Diffusion model for P450 generation",
"url": "https://spj.science.org/doi/10.34133/research.0413"
}
]
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Illinois at Urbana-Champaign",
"pi": "Huimin Zhao",
"image": "images/processed/Huimin-Zhao.jpg",
"website": "https://zhaogroup.chbe.illinois.edu/index.html",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "UNC Chapel Hill",
"pi": "Huong Kratochvil",
"image": "images/processed/Huong-Kratochvil.jpg",
"website": "https://www.kratochvillab.com/",
"papers": [],
"keywords": "Membrane protein design, functional protein design, molecular recognition, immune response.",
"about": "This research focuses on de novo protein design to test fundamental principles of molecular recognition, particularly in membrane transport and immune response. The lab seeks to engineer functional proteins to investigate structure-function relationships.",
"hiringStatus": "open",
"jobsUrl": "https://www.kratochvillab.com/meet-the-team/how-to-join"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Alabama at Birmingham",
"pi": "Hy Truong Son",
"website": "https://people.cs.uchicago.edu/~hytruongson/",
"papers": []
},
{
"region": "Global",
"country": "\ud83c\uddf8\ud83c\uddea Sweden",
"institution": "Lund University",
"pi": "Ingemar Andre",
"website": "https://andrelab.lu.se/",
"papers": [],
"keywords": "Protein modeling, symmetric protein complexes, self-assembly, computational design, structural biology.",
"about": "Large protein complexes self-assemble into functional structures. This research develops computational methods to predict and design novel protein assemblies, advancing structural biology and protein engineering. Experimental validation ensures accuracy, applying self-assembly principles to both natural and synthetic systems.",
"hiringStatus": "open",
"jobsUrl": "https://andrelab.lu.se/index.php/about/join"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Massachusetts Institute of Technology",
"pi": "James J. Collins",
"website": "https://www.collinslab.mit.edu/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://www.collinslab.mit.edu/"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Brigham Young University",
"pi": "James Moody",
"website": "https://labs.chem.byu.edu/moody-lab/about-us",
"papers": [],
"keywords": "Protein modeling, enzyme engineering, protein complexes, crystallization chaperones, protein polymers, structural enzymology, protein crystallization.",
"about": "This research applies protein modeling and engineering to understand enzymes and protein complexes, and to engineer new enzymes, protein polymers, and crystallization chaperones. The lab also uses structural enzymology to study enzyme mechanisms and develop tools to facilitate protein crystallization."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Stanford University",
"pi": "James Zou",
"website": "https://www.james-zou.com/",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Delaware",
"pi": "Jason Gleghorn",
"website": "https://www.gleghornlab.com/",
"papers": []
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Notre Dame of Maryland University",
"pi": "Jason Labonte",
"website": "https://www.ndm.edu/directory/jason-labonte",
"papers": [],
"keywords": "Computational modeling, carbohydrates, post-translational modifications (PTMs), protocol development, data mining, organic chemistry, biochemistry.",
"about": "This research focuses on developing computational methods to decode cellular interactions at the chemical level, emphasizing carbohydrates and post-translational modifications (PTMs). The lab employs protocol development, data mining, and experimental validation. Students gain skills in organic chemistry, biochemistry, and computational modeling to advance understanding of biochemical processes.",
"hiringStatus": "closed",
"jobsUrl": "https://www.ndm.edu/directory/jason-labonte"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "John Hopkins University",
"pi": "Jeffrey J. Gray",
"website": "https://graylab.jhu.edu/",
"papers": [],
"keywords": "Protein docking, antibody engineering, glycoproteins, membrane proteins, Rosetta, computational modeling, protein-surface interactions, disease research.",
"about": "This research focuses on computational protein structure prediction and design, with expertise in protein docking, antibody engineering, and membrane protein modeling. The lab develops tools like RosettaDock, RosettaAntibody, and PyRosetta to tackle challenges such as conformational changes upon binding and energy calculations. Collaborations span diverse biomedical areas, including cancer, Alzheimer's disease, antibiotic resistance, and autoimmune disorders.",
"hiringStatus": "open",
"jobsUrl": "https://graylab.jhu.edu/resources.php"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "UC Berkeley",
"pi": "Jennifer Doudna",
"website": "https://doudnalab.org/",
"papers": [],
"hiringStatus": "closed",
"jobsUrl": "https://doudnalab.org/"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "UC Berkeley",
"pi": "Jennifer Listgarten",
"website": "http://www.jennifer.listgarten.com/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "http://www.jennifer.listgarten.com/group.html#students"
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Vanderbilt University",
"pi": "Jens Meiler",
"website": "https://meilerlab.org/",
"papers": [],
"keywords": "Protein-ligand interactions, computational modeling, drug design, membrane proteins, structure elucidation, experimental validation, protein structure.",
"about": "This research combines computational and experimental approaches to study protein-ligand interactions. The lab develops computational methods for elucidating membrane protein structures, designing specific therapeutic molecules, and enhancing drug specificity. Predictions are experimentally validated within the lab or through collaborations, ensuring practical applications for structural biology and targeted drug development.",
"hiringStatus": "open",
"jobsUrl": "https://meilerlab.org/research-opportunities-in-chemical-and-structural-biology/"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Arizona State University",
"pi": "Jeremy Mills",
"website": "https://search.asu.edu/profile/2695303",
"papers": [],
"keywords": "Protein design, fluorescent proteins, non-canonical amino acids, fluorogenic probes, protein-protein interactions, metalloproteins, enzyme engineering.",
"about": "This research focuses on designing proteins that incorporate fluorescent or fluorogenic non-canonical amino acids. The lab engineers proteins to serve as fluorescent reporters for protein-protein, protein-small molecule, and protein-metal interactions. Additional projects involve designing novel functional metalloproteins and enzymes.",
"hiringStatus": "closed",
"jobsUrl": "https://search.asu.edu/profile/2695303"
},
{
"region": "Asia",
"country": "\ud83c\uddf0\ud83c\uddf7 South Korea",
"institution": "Korea Advanced Institute of Science & Technology",
"pi": "Ji-Joon Song",
"website": "https://www.song-kaist.org",
"papers": []
},
{
"region": "North America",
"country": "\ud83c\udde8\ud83c\udde6 Canada",
"institution": "Mila - Quebec AI Institute",
"pi": "Jian Tang",
"website": "https://jian-tang.com/",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Fudan University",
"pi": "Jianpeng Ma",
"website": "https://mrics.fudan.edu.cn/info/1021/1110.htm",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Westlake University",
"pi": "Jianyang Zeng",
"website": "https://aicb.lab.westlake.edu.cn/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://aicb.lab.westlake.edu.cn/Openings.htm"
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Shandong University",
"pi": "Jianyi Yang",
"website": "https://yanglab.qd.sdu.edu.cn/",
"papers": [],
"keywords": "Structure prediction, cryo-EM, artificial intelligence, trRosetta, trRosettaRNA, I-TASSER.",
"about": "This lab develops computational methods for predicting protein and RNA structures, contributing significantly to methods such as trRosetta, trRosettaRNA, and I-TASSER. Research incorporates cryo-EM data and AI techniques.",
"hiringStatus": "open",
"jobsUrl": "https://yanglab.qd.sdu.edu.cn/positions.html"
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "Tsinghua University",
"pi": "Jianzhu Ma",
"website": "https://majianzhu.com/",
"papers": []
},
{
"region": "Asia",
"country": "\ud83c\udde8\ud83c\uddf3 China",
"institution": "ShanghaiTech University",
"pi": "Jiayi Dou",
"website": "https://slst.shanghaitech.edu.cn/djy/",
"papers": [],
"keywords": "De novo protein design, neuroscience, light-sensitive proteins, ion channels, membrane fusion, optogenetics.",
"about": "This lab designs de novo proteins, including light-responsive proteins, ion channels, and membrane fusion systems, to develop tools for neuroscience research. Using computational design and deep learning, the lab creates novel protein-based approaches to study and modulate brain activity."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "New York University",
"pi": "Jin Kim Montclare",
"website": "http://montclare.poly.edu/",
"papers": []
},
{
"region": "EMEA",
"country": "\ud83c\udde8\ud83c\uddff Czech Republic",
"institution": "Masaryk University",
"pi": "Jiri Damborsky",
"image": "images/processed/Jiri-Damborsky.jpg",
"website": "https://loschmidt.chemi.muni.cz/peg/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://loschmidt.chemi.muni.cz/peg/positions/"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of Kansas",
"pi": "Joanna Slusky",
"website": "https://molecularbiosciences.ku.edu/people/joanna-slusky",
"papers": [],
"keywords": "Membrane proteins, computational protein design, protein characteristics, membrane protein design, protein-membrane interactions.",
"about": "The Slusky lab studies outer membrane proteins, identifying their common structural features and designing new membrane proteins for practical applications such as diagnostics, therapeutics, and environmental remediation."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Stanford University",
"pi": "Jure Leskovec",
"website": "https://cs.stanford.edu/people/jure/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://snap.stanford.edu/"
},
{
"region": "Global",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "University of California, Davis",
"pi": "Justin Siegel",
"website": "https://siegel.ucdavis.edu/",
"papers": [],
"keywords": "Computational enzyme design, enzyme catalysis, genetic methods, chemical methods, novel catalysts.",
"about": "This lab uses computational, genetic, and chemical methods to design novel enzyme catalysts. The research addresses modern challenges in food, energy, and health by developing tailored enzymes with new catalytic properties for practical applications."
},
{
"region": "North America",
"country": "\ud83c\uddfa\ud83c\uddf8 United States",
"institution": "Wake Forest University",
"pi": "Katherine I. Albanese",
"website": "https://www.albaneselab.com/",
"papers": [],
"hiringStatus": "open",
"jobsUrl": "https://www.albaneselab.com/contact"
},
{
"region": "Asia",
"country": "\ud83c\uddf0\ud83c\uddf7 South Korea",
"institution": "Korea Institute of Science and Technology",
"pi": "Keunwan Park",